THE DIVERSITY OF SERUM ANTI-DSG3 IGG SUBCLASSES HAS A MAJOR IMPACT ON PEMPHIGUS ACTIVITY AND IS PREDICTIVE OF RELAPSES AFTER TREATMENT WITH RITUXIMAB

IntroductionWe studied the distribution and in vitro pathogenicity of anti-DSG3 IgG subclasses during the course of pemphigus vulgaris (PV).MethodsWe longitudinally studied the distribution of anti-DSG3 IgG subclasses (before versus after treatment) in sera from PV patients, using an addressable-laser bead immunoassay (ALBIA).The in vitro pathogeni

Genome sequencing (GS) provides exciting opportunities to rapidly identify a diagnosis in critically ill newborns and children with rare genetic conditions.Nevertheless, there are reasons to remain cautious about the use of GS.Studies to date have been mostly in highly selected populations of babies with unusual clinical presentations.GS leads to d

Background/Aims: Doxorubicin is a widely used chemotherapeutic agent, but its clinical use is restricted because of a high risk of cardiotoxicity.Bone marrow-derived mesenchymal stem cells (BMSCs) may repair ischaemically damaged myocardium through transdifferentiation and paracrine action.The aim of this study is to investigate if doxorubicin caus

This paper defines four modes of tutorials created ad hoc in order to develop a specific experience of Learning Project (APP), in the Bachelor of Advertising and Public Relations from the University of Girona.The project has been based on the development of a comprehensive communication campaign from an actual concrete custom client, in this case,

Alkaline soils commonly called as Usar soil having pH 7.5 to 11.0 is Footwear commonly found in regions having poor drainage and little percolation.These soils occupy vast tracts of barren lands in the northern parts of India.These areas are frequently visited by man and animals, however there are no reports on the occurrence of keratinophilic fung